ABSTRACT
The coronavirus 2 illness (Covid-19) global pandemic has resulted in severe infection causing fever, cough, shortness of breath, pneumonia and even death. WHo is monitoring intimately in coordination with scientific experts and government agencies, the transmission rate of this virus and its neoteric variants identified worldwide. Since the start of year 2020, all the health authorities of each country are working in collaboration to explore the scientific information on coronavirus and providing essential guidelines to save humans. Undoubtedly, this pandemic impacted many lives regardless of all preventive steps followed to minimize its transmission. Currently, multiple anti Covid-19 vaccines are available everywhere and government authorities are monitoring and providing the guidelines for taking booster dose of vaccine to minimize and control the transmission of different variants of this virus. it is rational to state that some of the available anti Covid-19 vaccines may not be highly efficient against new emerging variants so further investigation and research are the need of hour. Therefore, the present review portrayed the features of the novel variants and mutations of coronavirus 2 (Covid-19) and therapeutic updates associated with the effectiveness of different vaccines against new strains reported worldwide. Copyright © 2022 Oriental Scientific Publishing Company. All rights reserved.
ABSTRACT
The Covid-19 pandemic since 2019 has imparted a massive influence on the human life around the world, irrespective of all the precautionary measures followed worldwide it is strongly suggested that only the effective and safer vaccine can control this vicious pandemic. Nevertheless, the vaccine development strategies for Covid-19 was initiated firstly in china after the outbreak of Covid-19 and then globally after it was declared as pandemic by World Health Organization. Currently, numerous platforms have been designed for developing the most efficacious and safe vaccines designed by different technologies including protein subunit, viral vector, RNA, DNA, inactivated, and live attenuated approach. Here, this review will illustrates the detailed information on above mentioned Covid-19 vaccines development technologies, protocols and their clinical trial phase status. Additionally, this review also includes the details of vaccines failed to progress further.